Moxidectin
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rpetersen
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- Posts: 83
- Joined: 28 May 2012, 18:00
- Location: South Africa, Cape Town
I am totaly confused now after following the ACV thread. It then turns to moxidectin. What is the proper dosage for Moxidectin. I know 5ml - ltre of water. Direct orally 
one drop as per Dr Walkers website or on the skin. 
Riyaad
one drop as per Dr Walkers website or on the skin. Riyaad
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Myzomela
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- Posts: 1545
- Joined: 24 Jan 2011, 18:44
- Location: Melbourne Vic
I'll try to clear this up.
Ivermectin is the first released product in this group of drugs which was originally marketed for worming & controlling external parasites in farm animals, and was then used in birds.
Moxidectin was the next-generation product- similar but more advanced. It had a broader mode of action killing a wider range of worms more effectively. The oral version also mixed well in water, whereas even the oral ivermectin did not. I disagree that its safety margin is not as good as ivermectin- I have used it at vey high doses safely.
The problem with these drugs is that there are lots of different preparations available of different concentrations designed for different animals. Some are oral, some are topical (pour-on) and some are injectable.
Most of the ones used for birds are oral forms designed for sheep and goats etc.
If using these preparations which contain moxidectin at a concentration of 2mg/ml, then 5mls per litre drinking water is the ideal in-water dose.
One "drop" per finch is given as the direct dose rate because of the difficulty of measuring the direct dose for a bird as small as a finch (actual dose is approx 0.01mls per 15 gm finch). These direct doses should be given direct to beak. If you apply it topically on the back of the neck the absorption is more variable- it works really well for budgies with scaly face mites but I'm not convinced how well it works for worming/air sac mites.
If you want the spot on preparation you are better off using ivermectin diluted with propylene glycol, but that's a whole different topic!
In summary:
In-water dose of moxidectin (2 mg/ml concentration): 5 ml/L drinking water ;
direct dose: 1 drop/finch or 0.01 mls direct to beak of the moxidectin concentrate
Ivermectin is the first released product in this group of drugs which was originally marketed for worming & controlling external parasites in farm animals, and was then used in birds.
Moxidectin was the next-generation product- similar but more advanced. It had a broader mode of action killing a wider range of worms more effectively. The oral version also mixed well in water, whereas even the oral ivermectin did not. I disagree that its safety margin is not as good as ivermectin- I have used it at vey high doses safely.
The problem with these drugs is that there are lots of different preparations available of different concentrations designed for different animals. Some are oral, some are topical (pour-on) and some are injectable.
Most of the ones used for birds are oral forms designed for sheep and goats etc.
If using these preparations which contain moxidectin at a concentration of 2mg/ml, then 5mls per litre drinking water is the ideal in-water dose.
One "drop" per finch is given as the direct dose rate because of the difficulty of measuring the direct dose for a bird as small as a finch (actual dose is approx 0.01mls per 15 gm finch). These direct doses should be given direct to beak. If you apply it topically on the back of the neck the absorption is more variable- it works really well for budgies with scaly face mites but I'm not convinced how well it works for worming/air sac mites.
If you want the spot on preparation you are better off using ivermectin diluted with propylene glycol, but that's a whole different topic!
In summary:
In-water dose of moxidectin (2 mg/ml concentration): 5 ml/L drinking water ;
direct dose: 1 drop/finch or 0.01 mls direct to beak of the moxidectin concentrate
Research; evaluate;observe;act
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wagga
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- Posts: 678
- Joined: 24 Apr 2010, 22:08
- Location: Port Macquarie NSW 2444
- Location: PORT MACQUARIE NSW
A big thumbs up. 
The AFF is so lucky to have members who openly share theirwealth of knowledge and professional expertise to others.
The AFF is so lucky to have members who openly share theirwealth of knowledge and professional expertise to others.
Life in Port Macquarie is the ultimate Aussie sea change lifestyle.
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Myzomela
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- Posts: 1545
- Joined: 24 Jan 2011, 18:44
- Location: Melbourne Vic
I'm glad some people have found it helpful.
As you say, that's what the AFF is all about, sharing the information. We all benefit from what's posted on this site. I learn new things every day, too. Win-win really!
As you say, that's what the AFF is all about, sharing the information. We all benefit from what's posted on this site. I learn new things every day, too. Win-win really!
Research; evaluate;observe;act
