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Re: A sweetener for Wormout Gel

Posted: 17 Aug 2012, 19:55
by Myzomela
...because it is the only product that combines oxfendazole with praziquantel...
and thus provides a good change from moxidectin or ivermectin based wormers. Oxfendazole is quite safe and effective.
If only they could make it more palatable!
It doesn't matter how good a wormer it is if they won't drink it!

Re: A sweetener for Wormout Gel

Posted: 18 Aug 2012, 08:46
by jusdeb
true true and very true .
It makes a good alternative to prevent worms getting immune to the same drugs however ....... as I said before my birds held on for 2 days to drink rather than drink the stuff ...bad enough in winter but could be fatal in summer .

Re: A sweetener for Wormout Gel

Posted: 18 Aug 2012, 16:47
by garyh
Having trouble getting this through my thick brain ,if i use moxi to worm my birds and it rids them of them so their worm free ,then how do the worms get use to the medication,and if moxi rids them of worms and the birds take it readily then why do you change medications to something that has oxfendasole with praziquantel and tastes terrible,does it do a better job,does it work quicker and after using this unpalatable stuff do i then have to use say moxi so the worms dont get use to it,garyh

Re: A sweetener for Wormout Gel

Posted: 18 Aug 2012, 17:27
by VR1Ton
The same reason we don't take the same antibiotic over & over. Not all worms are killed by the initial dose, so they can tolerate the medication, these organisms then reproduce, producing more tolerant organisms, these then multiply giving a population resistant to the treatment. Alternating between 2 or more medications will reduce the chance of organisms becoming resistant. Just look at mice & ratsack, you may as well pee on them, just as much chance of killing them.

Re: A sweetener for Wormout Gel

Posted: 18 Aug 2012, 17:51
by Myzomela
I'm sure your head is not that thick Gary! :D

VR1Ton has answered it perfectly.

The reasons that we don't get 100% kill rates are varied, including:
1) natural variation in sensitivites to a drug within a parasite population;
2)variable intake of the drug; dosing any bird through the drinking water is very inefficient as intake depends on taste, ambient temperature and humididty, availability of other water sources (eg rain, greenfood), how well the drug mixes in the water; drug breakdown due to sunlight etc
3) interactions of the drug with other chemicals, foods and minerals in the body.
4) Many aviary environments actually favour survival of the parasite's eggs ie organic matter on the floor, moisture so that reinfection from the aviary environment is almost immediate.

In reality, we use these drugs very inefficiently; therefore, rotating the groups of wormers we use will hopefully delay the onset of resistance.

Re: A sweetener for Wormout Gel

Posted: 18 Aug 2012, 18:44
by garyh
OH yes it is ,if you listen to the wife ,thanks for the info Myzo and VRITON ,good to know i need to use more than one medication and that they only partially work,will be a good conversation next time im at the vets,thanks garyh